---
title: Repetitive GON Blockade for Menstrual Migraine | PMS & PMDD trial
description: Completed. Clinical trial on Menstrual Migraine and Menstrually Related Migraine run by Saglik Bilimleri Universitesi in Turkey (Türkiye).
url: https://niyora.com/research/trials/repetitive-gon-blockade-for-menstrual-migraine-nct07576309/
---

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- Repetitive GON Blockade for Menstrual Migraine

Completed

# Repetitive GON Blockade for Menstrual Migraine

Perimenstrual Repetitive Greater Occipital Nerve Blockade for Menstrual Migraine: A Randomized, Double-Blind, Placebo-Controlled Trial

Status Completed Registry ID NCT07576309 Type Interventional (tests a treatment) Phase NA Conditions Menstrual Migraine, Menstrually Related Migraine What is tested 0.5% bupivacaine (drug); Normal Saline (other) Sponsor Saglik Bilimleri Universitesi Where Turkey (Türkiye) Participants 48 Start 2024-10-19 Completion 2025-11-30 Last update 2026-05-08

## About the study

: The primary objective of this prospective, randomized, double-blind, placebo-controlled clinical trial is to evaluate whether repetitive bilateral greater occipital nerve (GON) blockade administered with a local anesthetic (0.5% bupivacaine) significantly reduces headache severity, attack duration, and the number of pain days in female patients with menstrual migraine compared to a placebo group (normal saline). Patients will receive injections twice a month for three months (seven days before the expected onset of menstruation and on the first day of menstruation).

Summary from ClinicalTrials.gov.

[See the full record](https://clinicaltrials.gov/study/NCT07576309)

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