Non-randomised trial, 1984
Does lithium help with premenstrual tension?
Case reports suggested it might help, but well-designed research studies found no benefit.
What they did
Literature review of clinical trials testing lithium in approximately 14 medical conditions, including premenstrual tension. The review examined both case reports and controlled research studies.
What they found
Many case reports showed lithium was effective for premenstrual tension. However, well-designed and controlled research studies showed negative results overall.
What it means for you
Early case reports were optimistic about lithium for PMS, but rigorous research studies did not confirm benefit. This shows why controlled studies are more reliable than individual case reports.
14
medical conditions reviewed
About the study
- Original title
- A review of clinical trials of lithium in medicine
- Authors
- Yung CY
- Journal
- Pharmacology, biochemistry, and behavior
- Year
- 1984
- Study design
- Non-randomised trial
- What was tested
- None - literature review
- Read the paper
- doi.org/10.1016/0091-3057(84)90163-1
Topics
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