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Survey study, 2014

Do women whose depression started early experience more premenstrual symptoms?

Yes. Women with depression that started at an earlier age were more likely to have premenstrual symptoms. Because data was collected by recall, we cannot be sure about timing or whether premenstrual symptoms came before or after the depression.

Moderate study design 6017 Han Chinese women with recurrent major depression

What they did

Analysis of data from the CONVERGE project studying Han Chinese women with recurrent major depression. Combined analysis of 6017 women total (1848 in phase I and 4169 in phase II). Used regression models to find associations between age depression started and various clinical features including premenstrual symptoms.

What they found

Women whose depression began at an earlier age showed more severe, recurrent and chronic illness, higher neuroticism, greater family history of mental illness and more psychiatric comorbidity. Earlier depression onset was associated with premenstrual symptoms and postpartum depression, but a lower likelihood of melancholia.

What it means for you

There may be a link between depression starting early and experiencing premenstrual symptoms, possibly due to shared biological factors. However, the study relied on women recalling when their depression started, which can be unreliable. This studied only Han Chinese women so findings may not apply elsewhere.

6017

total women studied

1848

phase I participants

4169

phase II participants

About the study

Original title
Age at onset of recurrent major depression in Han Chinese women - a replication study
Authors
Yang F, Zhao H, Wang Z et al.
Journal
Journal of affective disorders
Year
2014
Study design
Survey study
Participants
6,017

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