Case-control study, 1994
Do women with a history of PMS have higher risk of osteoporosis?
Women who had PMS symptoms or irregular periods in the past were more likely to develop osteoporosis after menopause. However, because women had to remember their past symptoms years later, the accuracy of these results is uncertain.
What they did
Compared 75 postmenopausal women with osteoporosis to 77 similar women without osteoporosis. Researchers asked them to recall their past PMS and irregular periods, and about hot flushes during menopause.
What they found
Women with osteoporosis were significantly more likely to have had PMS symptoms and irregular periods. They were also more likely to remember having severe or long-lasting hot flushes at menopause.
What it means for you
PMS or irregular periods earlier in life might be linked to higher osteoporosis risk later. The main limitation is that women had to remember symptoms from years ago, which may not be reliable.
1.86
Osteoporosis risk with history of PMS
3.08
Osteoporosis risk with irregular periods
1.35
Osteoporosis risk with menopausal hot flushes
About the study
- Original title
- An association between osteoporosis and premenstrual symptoms and postmenopausal symptoms
- Authors
- Lee SJ, Kanis JA
- Journal
- Bone and mineral
- Year
- 1994
- Study design
- Case-control study
- What was tested
- None - observational study based on recall
- Read the paper
- doi.org/10.1016/s0169-6009(08)80150-x
Topics
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