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Review, 2022

What causes severe PMS and what treatments work?

Severe PMS is caused by hormone changes and brain chemistry problems. Treatments that stop ovulation with hormones or increase serotonin with SSRIs both reduce symptoms.

Strong study design Not applicable (systematic review)

What they did

Reviewed research on severe PMS symptoms, their causes, and available treatments.

What they found

Severe PMS affects 5-8% of women, and the majority with severe PMS also match the criteria for PMDD. The most bothersome symptoms affect mood and behavior, including irritability, tension, depression, weepiness, and mood swings, though physical symptoms like breast soreness and bloating also occur. Treatments that stop ovarian cyclicity using GnRH analogues or estradiol patches or implants successfully reduce symptoms. Serotonin reuptake inhibitors are also helpful, whether used continuously or just during the luteal phase.

What it means for you

Severe PMS has two main treatment approaches targeting different causes: hormonal and brain chemistry. Understanding which cause applies to you can help guide treatment choices. This is a review of existing research.

5-8%

women with severe PMS

About the study

Original title
AN OVERVIEW ON PREMENSTRUAL SYNDROME
Authors
Mrs. Deepa. H. S, Sherene G Edwin
Journal
IDC International Journal
Year
2022
Study design
Review
What was tested
Hormonal treatments and serotonin reuptake inhibitors
Open access
Yes

Topics