Review, 1997
Which antidepressants are most effective for premenstrual dysphoric disorder?
Selective antidepressants that work on serotonin are consistently the most effective. Most studies used daily treatment, but intermittent dosing needs more research.
What they did
Literature review of antidepressant treatment research for premenstrual dysphoria over several decades.
What they found
Selective antidepressants, particularly those active at serotonin receptors, showed the most consistent positive results. PMDD is diagnosed by at least five symptoms including at least one mood symptom, with impairment prospectively confirmed.
What it means for you
Serotonin-based antidepressants are the main proven treatment for PMDD. The main limitation is that most studies used daily dosing, so intermittent dosing needs more research.
5
Minimum symptoms for PMDD diagnosis
About the study
- Original title
- Antidepressants in the treatment of premenstrual dysphoric disorder
- Authors
- Yonkers KA
- Journal
- The Journal of clinical psychiatry
- Year
- 1997
- Study design
- Review
- What was tested
- Selective antidepressants active at serotonin receptors
- Read the paper
- https://pubmed.ncbi.nlm.nih.gov/9418742/
Topics
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