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Cohort study, 2014

Do sex hormones affect women's cognitive functions across the menstrual cycle?

No. Changes in estrogen and progesterone did not affect memory, learning, or thinking abilities. Cognitive performance remained stable across the cycle.

Early or limited evidence 16 young healthy female medical students (average age 21.56 years) with no history of menstrual, psychiatric, or neurological disorders

What they did

16 young healthy female medical students with an average age of 21.56 years took cognitive tests at three cycle phases: early follicular, ovulatory, and mid-luteal. Blood hormone levels were measured and timing was verified using a specific hormone peak.

What they found

Most women performed above average on cognitive tests. There were no significant changes in immediate memory, working memory, delayed recall, verbal learning, delayed verbal learning, or verbal fluency at any cycle phase. Test results did not correlate with measured hormone levels.

What it means for you

Everyday thinking and memory abilities may not change with the menstrual cycle in healthy young women. The main limitation is that this is a very small, homogeneous group of medical students with no health problems, so findings may not apply to all women.

16

women studied

21.56

average age in years

3

cycle phases tested

About the study

Original title
Basic cognitive functions across the menstrual cycle in a controlled female cohort
Authors
Mihalj M, Drenjančević I, Včev A et al.
Journal
Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina
Year
2014
Study design
Cohort study
Participants
16
What was tested
None

Topics