Randomised trial, 1983
Is bromocriptine effective for premenstrual syndrome?
No substantial evidence that bromocriptine works for premenstrual syndrome overall. It may help breast pain if the dose is at least 5 mg daily.
What they did
A survey of 14 placebo-controlled studies that tested bromocriptine for premenstrual symptoms.
What they found
No substantial support for bromocriptine as an effective treatment for premenstrual syndrome. Irritability, depression, and anxiety were not significantly improved with bromocriptine compared to placebo. Bromocriptine appeared effective for premenstrual breast pain (mastodynia) if the daily dose was at least 5 mg.
What it means for you
Bromocriptine doesn't seem to help most premenstrual symptoms, though it might relieve breast pain at higher doses. This review of 14 studies provides evidence across multiple trials, though the studies reviewed are relatively old.
14
Placebo-controlled studies reviewed
5 mg
Minimum daily dose for breast pain relief
About the study
- Original title
- Bromocriptine and premenstrual symptoms: a survey of double blind trials
- Authors
- Andersch B
- Journal
- Obstetrical & gynecological survey
- Year
- 1983
- Study design
- Randomised trial
- What was tested
- Bromocriptine versus placebo
- Read the paper
- doi.org/10.1097/00006254-198311000-00001
Topics
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