Skip to content

Cohort study, 2014

Does childhood abuse increase the risk of PMS in adulthood?

Yes, women with childhood emotional abuse had 2.6 times higher PMS risk, and those with physical abuse had 2.1 times higher risk. This 14-year prospective study provides strong evidence.

Strong study design Women aged 27-44 at baseline, free from PMS initially, from Nurses' Health Study 2

What they did

Prospective cohort study (Nurses' Health Study 2) of 1,018 women who developed PMS and 2,277 comparison women who remained free of PMS over 14 years. At baseline, all women were aged 27-44 and free of PMS. In 2001, participants reported their history of early life emotional, physical and sexual abuse.

What they found

Compared to women reporting no emotional abuse, those reporting the highest level of emotional abuse had 2.6 times the risk of PMS (95% CI 1.7-3.9, pTrend<0.0001). Women reporting severe childhood physical abuse had an odds ratio of 2.1 (95% CI 1.5-2.9, pTrend<0.001) compared to those with no physical abuse. Sexual abuse showed less strong associations. Findings remained similar after adjusting for obesity, smoking and other factors.

What it means for you

Childhood trauma, particularly emotional and physical abuse, is associated with increased risk of PMS in middle reproductive years. The persistence of these findings after controlling for confounding factors suggests that trauma may directly affect PMS risk rather than just being associated with other risk factors like smoking or obesity.

2.6

times higher risk for highest emotional abuse (95% CI 1.7-3.9)

2.1

odds ratio for severe physical abuse (95% CI 1.5-2.9)

14

years of follow-up

About the study

Original title
Early life emotional, physical, and sexual abuse and the development of premenstrual syndrome: a longitudinal study
Authors
Bertone-Johnson ER, Whitcomb BW, Missmer SA et al.
Journal
Journal of women's health (2002)
Year
2014
Study design
Cohort study
Participants
2,277
What was tested
None; observational study of childhood abuse and PMS risk
Open access
Yes

Topics