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Study, 2003

Can a specific birth control pill help with PMS symptoms?

Yes. In this study, 80% of women taking a pill containing drospirenone and ethinylestradiol reported improvement, and 75% said they were satisfied with the treatment.

Moderate study design 336 women with psychological, behavioral, and physical premenstrual symptoms

What they did

336 women with PMS symptoms took an oral contraceptive containing 3 mg drospirenone and 30 micrograms ethinylestradiol (Yasmin) for six 28-day cycles. Researchers measured mood, physical symptoms like bloating and breast tenderness, and body weight.

What they found

Mood improved by cycle 3 and stayed improved at cycle 6. There was a clear reduction in bloating and breast tension. 80% of the women improved on treatment. 75% of women said they were satisfied. Body weight stayed the same or decreased slightly. The pill provided good cycle control.

What it means for you

This pill appears to help with PMS symptoms including mood and bloating. However, this study had no comparison group (no women received a placebo), so some improvement might be from expecting to feel better rather than from the pill itself. A larger study comparing this pill to a placebo would give stronger evidence.

336

Women enrolled

80%

Reported improvement on treatment

75%

Satisfied with treatment

About the study

Original title
Effect of an oral contraceptive containing drospirenone and ethinylestradiol on general well-being and fluid-related symptoms
Authors
Apter D, Borsos A, Baumgärtner W et al.
Journal
The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception
Year
2003
Study design
Study
Participants
336
What was tested
Drospirenone 3 mg and ethinylestradiol 30 micrograms oral contraceptive (Yasmin) for six 28-day cycles

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