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Non-randomised trial, 2025

Do cashew nuts help reduce PMS symptoms by increasing serotonin?

Women who ate 70 grams of cashew nuts daily for 2 weeks showed increases in serotonin and reductions in PMS symptoms compared to women who did not eat them. The sample was small and lasted only 2 weeks, so we need more research to know if this works long-term.

Moderate study design 42 adolescents with PMS

What they did

Quasi-experimental study with control group. 42 adolescents with PMS. The intervention group ate 70 grams of cashew nuts per day for 2 weeks starting on day 14 of their menstrual cycle. The control group did not eat cashew nuts. Serotonin was measured from saliva samples, and PMS symptoms were measured with a questionnaire before and after.

What they found

The cashew nut group's serotonin increased from 158.91 ng/mL to 250.43 ng/mL. Their PMS symptom scores decreased from 26.57 to 17.38. In contrast, the control group's serotonin decreased from 123.7 ng/mL to 117.67 ng/mL, and their PMS symptoms increased from 27.8 to 28.23. The difference between groups was statistically significant (P<0.001).

What it means for you

Eating cashew nuts may help reduce PMS symptoms and increase serotonin. However, the study included only 42 adolescents, lasted just 2 weeks, did not randomly assign people to groups, and used a very small sample, so we cannot be certain this works for all women or longer-term.

70 grams/day

cashew nuts dose

2 weeks

duration of intervention

158 to 250 ng/mL

serotonin increase in intervention group

About the study

Original title
Effect of cashew nut consumption on salivary serotonin levels in adolescents with premenstrual syndrome
Authors
Dian P. HASBA, Aryadi Arsyad, Elizabet Catherine Jusuf
Journal
Gazzetta Medica Italiana Archivio per le Scienze Mediche
Year
2025
Study design
Non-randomised trial
Participants
42
What was tested
70 grams of cashew nuts daily for 2 weeks on days 14-28 of menstrual cycle

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