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Randomised trial, 2018

Does evening primrose help premenstrual syndrome?

Yes. Evening primrose 1000 mg twice daily for 2 months significantly reduced PMS severity compared to placebo, with few side effects.

Moderate study design 80 female university students with premenstrual syndrome in Iran

What they did

Double-blind RCT with 80 female university students with PMS in Iran, randomly divided into two groups of 40. One group received evening primrose 1000 mg twice daily, the other received placebo for 2 months. Symptoms were assessed with daily symptom records and questionnaires.

What they found

PMS severity was significantly reduced in the evening primrose group, dropping from 61.45±21.25 to 21.38±9.05 (p<0.05). The placebo group also improved but not as much. Few side effects were reported.

What it means for you

Evening primrose appears effective for reducing PMS severity with minimal side effects. The study was limited to university students in Iran so results may not apply to other populations. Overall symptom severity improved but we don't know which specific symptoms (like mood, pain, or bloating) improved most.

80

Participants

1000mg, 2x daily

Evening primrose dose

61.45 to 21.38

PMS severity score before/after

About the study

Original title
Effect Of Evening Primrose On Premenstrual Syndrome: A Randomized Clinical Trial
Authors
Seyedeh Zahra Masoumi Fatemeh Shobeiri
Journal
Zenodo (CERN European Organization for Nuclear Research)
Year
2018
Study design
Randomised trial
Participants
80
What was tested
Evening primrose 1000 mg, 2 times per day for 2 months
Open access
Yes
Original abstract

Premenstrual syndrome is a set of physical and emotional psychological symptoms which occur periodically during the secretory phase of the menstrual period. This study was done to effect of Evening Primrose on premenstrual syndrome. This clinical double-blind study was conducted on 80 girls student suffered from premenstrual syndrome at Hamadan University of Medical Sciences, Hamadan, Iran. The samples were then randomly divided in two 40- member groups, Evening Primrose (1000 mg, 2 times per day) and placebo (2 times per day) groups. The subjects were received the therapeutic regimen for 2 months. Data collection tools were collected using questionnaires, daily symptom records (DSR) questionnaires and adverse drug reaction questionnaires of participants before and after intervention were registered and compared. Analyses were carried out by Chi-square, paired t-test using SPSS /21.The result showed that after intervention, severity of premenstrual syndrome was reduced in Evening Primrose group (61.45±21.25 to 21.38±9.05) (P<0.05). Findings revealed that taking Evening Primrose can reduce severity of premenstrual syndrome. So, regarding the little side complications, consumption of Evening Primrose has a useful effect on premenstrual syndrome. Key words: Premenstrual Syndrome, Evening Primrose, Iran

Reproduced under CC-BY.

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