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Randomised trial, 2021

Does curcumin help with PMS and period pain?

Curcumin reduced PMS symptoms and period pain about as well as placebo did, suggesting it may not be more effective than placebo. The study cannot tell us if curcumin truly helps for sure.

Moderate study design Young women with both PMS and period pain.

What they did

A trial where 62 women took curcumin capsules and 62 took placebo. Everyone took one capsule daily from a week before their period until 3 days after it for three months.

What they found

Both groups improved significantly. Curcumin reduced period pain by 64 percent and placebo by 53.3 percent. PMS symptom scores fell from 32.5 to 21.6 in the curcumin group and from 31.7 to 23.4 in the placebo group.

What it means for you

Curcumin works about the same as a placebo for PMS and period pain, so any benefit may just be from expecting it to work. The study was relatively small and lasted only three months.

64%

period pain reduction with curcumin

53.3%

period pain reduction with placebo

32.5 to 21.6

PMS symptom score change with curcumin

About the study

Original title
Effects of curcumin on menstrual pattern, premenstrual syndrome, and dysmenorrhea: A triple-blind, placebo-controlled clinical trial
Authors
Bahrami A, Zarban A, Rezapour H et al.
Journal
Phytotherapy research : PTR
Year
2021
Study design
Randomised trial
Participants
62
What was tested
Curcumin 500 mg daily from 7 days before menstruation to 3 days after for three menstrual cycles.
Open access
Yes
Original abstract

Premenstrual syndrome (PMS) and primary dysmenorrhea are common complaints among young women. This study evaluated the effects of curcumin supplements on symptoms of pain in young women with PMS and dysmenorrhea. A randomized, triple-blinded, placebo-controlled clinical trial was undertaken. Women who suffered from both PMS and dysmenorrhea were enrolled, and were randomly allocated to the curcumin (n = 62), or placebo (n = 62) groups. Each subject received one capsule (500 mg of curcuminoid, or placebo) daily, from 7 days pre- until 3 days post-menstruation for three successive menstrual cycles. Participants recorded the severity of PMS, or dysmenorrhea using a Premenstrual Syndrome Screening Tool (PSST) and the visual analog scale, respectively. Baseline characteristics of participants did not differ between the curcumin and placebo groups. At the end of the trial, the PSST scores were significantly lower in both the curcumin (32.5 ± 9.8 vs. 21.6 ± 9.8); and placebo groups (31.7 ± 9.4 vs. 23.4 ± 12.8). There was a significant reduction of dysmenorrhea pain in both the curcumin and placebo groups (by 64% and 53.3%, respectively). Hence, curcumin had comparable effects as placebo, regarding the amelioration of symptoms of PMS and dysmenorrhea. Further studies are required with larger samples, using higher doses curcumin for longer durations, and perhaps in combination therapy.

Reproduced under CC-BY.

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