Skip to content

Randomised trial, 2023

Does curcumin help with sleep problems in women with PMS and period pain?

No. Both the curcumin and placebo groups improved similarly, with no significant difference between them.

Moderate study design 124 women with both PMS and dysmenorrhea (period pain)

What they did

124 women with both PMS and period pain took either 500 mg curcumin plus piperine or placebo daily from 7 days before until 3 days after their period for three menstrual cycles. Sleep problems were measured with questionnaires.

What they found

Insomnia and daytime sleepiness scores improved in both groups, but the improvement was the same in the curcumin group and placebo group. There was no significant difference between the two treatments.

What it means for you

Curcumin does not appear to work better than placebo for sleep problems in women with PMS and period pain. The improvement in both groups may have been due to placebo effect or natural variation over time.

124

women studied

500 mg

curcumin dose daily

3

menstrual cycles treated

About the study

Original title
Effects of curcumin supplementation on insomnia and daytime sleepiness in young women with premenstrual syndrome and dysmenorrhea: A randomized clinical trial
Authors
Seyedabadi S, Hoseini ZS, Ferns GA et al.
Journal
Avicenna journal of phytomedicine
Year
2023
Study design
Randomised trial
Participants
60
What was tested
500 mg curcumin plus piperine daily versus placebo, taken from 7 days before to 3 days after menstruation for 3 menstrual cycles
Open access
Yes
Original abstract

Objective: Premenstrual syndrome and primary dysmenorrhea are common gynecological complaints that are associated with psychological disorders. There is increasing evidence for the neuroprotective properties of curcumin, a polyphenolic natural product. This study aimed to assess the effects of curcumin on sleep complications in women with premenstrual syndrome and dysmenorrhea. Materials and methods: This triple-masked, placebo-controlled clinical trial comprised 124 patients with both premenstrual syndrome and dysmenorrhea. Participants were randomly assigned to curcumin (n=57) or control (n=60) groups. Each participant received one capsule containing either 500 mg of curcumin plus piperine or placebo, daily, from 7 days before until 3 days after menstruation for three consecutive menstrual cycles. Insomnia and sleepiness were assessed using standard questionnaires. Results: Scores for insomnia and daytime sleepiness were directly correlated with the Premenstrual Syndrome Screening Tool (PSST) score (p 0.05). There was a non-significant reduction in insomnia and sleepiness scores in both curcumin and placebo groups after the study intervention. Whilst, improvement rate of insomnia status, daytime sleepiness severity, short sleep duration and difficult sleep initiation was not statistically significant between the curcumin and placebo groups. Conclusion: Curcumin does not significantly affect sleep disorders in young women with premenstrual syndrome and dysmenorrhea.

Reproduced under CC-BY.

Topics