Survey study, 2022
What causes PMDD symptoms and how can they be treated?
Low progesterone is linked to PMDD symptoms. A medication called allopregnanolone and certain foods may help reduce symptoms.
What they did
Reviewed scientific literature and personal experience to understand how PMDD develops and what the physical and emotional symptoms are.
What they found
Low progesterone correlated with negative mood and physical symptoms in different phases of the menstrual cycle. Allopregnanolone (a type of medication) may reduce PMDD symptoms, and specific nutritional sources can help.
What it means for you
Doctors should understand how low progesterone causes PMDD and how allopregnanolone works as a treatment. This is a literature review rather than a study of actual patients, so the evidence is limited.
About the study
- Original title
- Every month: The result of premenstrual dysphoric disorders
- Authors
- Edna Aurelus
- Journal
- International Journal of Scientific Research Updates
- Year
- 2022
- Study design
- Survey study
- What was tested
- Allopregnanolone and nutritional sources
- Open access
- Yes
- Read the paper
- doi.org/10.53430/ijsru.2022.4.1.0127
Original abstract
Methods: Research was conducted using self-experience along with scientific literature findings to fully understand the physical and emotional syndromes of premenstrual dysphoric disorders (PMDD). Findings: Correlation with low progesterone in relation to negative affective and physical symptoms during the follicle and luteal phase were observed. Allopregnanolone, a neurosteroid, as a therapeutic agent can alleviate PMDD symptoms. Specific nutritional sources can also help alleviating the presenting symptoms. Conclusion: Awareness about PMDD symptoms is warranted in women experiencing them. Providers need to be familiar of the emotional and physical effect of low progesterone and the mechanism of action of Allopregnanolone in treating PMDD, when other interventions such as psychotherapy and other pharmacological intervention failed.
Reproduced under CC-BY.
Topics
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