Lab study, 2022
What type of premenstrual syndrome do women develop if they had problems during puberty?
In women with problematic puberty, psychological PMS (52%) was most common, followed by swelling (34%) and headaches (14%). Women with PMS had higher estradiol and progesterone levels than women without PMS.
What they did
Researchers studied women with premenstrual syndrome who experienced problems during puberty. They measured hormone levels (estradiol, progesterone, prolactin, androgens) and serotonin levels in the blood during the luteal phase of the cycle.
What they found
Psychological symptoms (52%) were most common, followed by swelling symptoms (34%) and headache symptoms (14%). Women with PMS had higher estradiol and progesterone during the luteal phase than healthy women. Progesterone levels correlated with symptom severity, with highest values in headache form and lowest in psychological form. Serotonin in women with psychological PMS was inversely related to severity. Prolactin and androgen levels did not differ between groups.
What it means for you
This identifies different PMS types in women with abnormal puberty. The hormone differences suggest estradiol and progesterone imbalances may contribute to PMS, which aligns with other research. However, the total number of women studied is unclear, making it difficult to know how broadly findings apply. Results may be specific to women with this type of puberty history.
52%
with psychological symptoms (neuropsychic form)
34%
with swelling symptoms (edematous form)
14%
with headache symptoms (cephalalgic form)
About the study
- Original title
- Features of pathogeny of premenstrual syndrome for women with a pathological pubertal period
- Authors
- О.А. Ковалишин
- Journal
- Perinatology and reproductology from research to practice
- Year
- 2022
- Study design
- Lab study
- Open access
- Yes
- Read the paper
- doi.org/10.52705/2788-6190-2022-02-4
Original abstract
The results of the conducted researches testify that neuropsycic form (52,0%) prevails in the structure of premenstrual syndrome, an oedematous form (34,0%) is less widespread, most rarely meeting is cephalgic form of disease (14,0%). Table of contents of estradiol and progesterone in the luteal phase of menstrual cycle in blood of patients by a premenstrual syndrome for certain higher, than for healthy women. The level of progesterone in blood of women with premenstrual syndrome correlates with weight of disease. The most high values of progesterone are present at cephalgic, most low – at the neuropsycic of disease. Table of contents of prolactin and androgens in blood of patients does not differ premenstrual syndrome from these indexes for healthy women. A table of contents of serotonin in blood of women with the neuropsycic form of premenstrual syndrome is in reverse dependence on the degree of weight of disease. The got results it must draw on at development of algorithm of diagnostic and treatment-and-prophylactic measures for patients with premenstrual syndrome.
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