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Survey study, 2006

Does the menstrual cycle affect how severe OCD symptoms are?

Yes. For many women with OCD, symptoms get worse before their period, with nearly half reporting this pattern. The menstrual cycle should be considered when assessing OCD severity.

Early or limited evidence 101 women with obsessive-compulsive disorder who completed a questionnaire

What they did

They sent questionnaires to 350 women with OCD and asked about symptom changes during the menstrual cycle, pregnancy, menopause, use of hormonal contraceptives, and medication. They asked women to rate their OCD symptom severity at three times during their menstrual cycle. 101 women completed and returned the questionnaire.

What they found

49 women reported that OCD symptoms got worse before their period. 9 women reported worsening during menopause. During pregnancy, 17 women reported symptoms got worse but 11 women reported symptoms got better.

What it means for you

For a large number of women with OCD, symptoms become more severe before the period, suggesting hormones affect OCD. The menstrual cycle should be tracked when assessing OCD severity. The study had a low response rate (only 29% of questionnaires were returned), so results may not represent all women with OCD.

49

Women reporting OCD worsening before period

101

Completed questionnaires returned

350

Total questionnaires sent

About the study

Original title
Female hormones affect symptom severity in obsessive-compulsive disorder
Authors
Vulink NC, Denys D, Bus L et al.
Journal
International clinical psychopharmacology
Year
2006
Study design
Survey study
Participants
17
What was tested
None

Topics