Review, 2003
Do GABA receptors and progesterone affect PMDD?
The review suggests they may be important based on animal studies, but does not provide specific conclusions about their role in PMDD in humans.
What they did
Review of animal models of depression and anxiety, and human clinical studies examining how neuroactive steroid hormones and GABA receptors relate to PMDD.
What they found
Animal models indicate that neuroactive steroid hormones and GABA receptors are important in mood disorders. The review discusses these findings in relation to human PMDD.
What it means for you
A brain chemical called GABA and the hormone progesterone may play a role in PMDD based on animal research, but the abstract does not provide specific evidence or conclusions. More research in humans is needed.
About the study
- Original title
- GABA receptors, progesterone and premenstrual dysphoric disorder
- Authors
- Sundström Poromaa I, Smith S, Gulinello M
- Journal
- Archives of women's mental health
- Year
- 2003
- Study design
- Review
- What was tested
- None (review article)
- Read the paper
- doi.org/10.1007/s00737-002-0147-1
Topics
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