Case-control study, 2024
Does weight loss surgery improve PMS symptoms in obese women?
Yes. Women with obesity and moderate-to-severe PMS who had sleeve gastrectomy surgery showed PMS improvement (57.35%) compared to women without surgery (25.40%) at 3 months follow-up.
What they did
Case-control study of 131 obese women in China with BMI at least 27.5 and moderate-to-severe PMS from 2018-2022. 68 chose laparoscopic sleeve gastrectomy surgery and 63 did not. PMS severity was measured at baseline and 3 months.
What they found
57.35% (39 women) in the surgery group had PMS improvement compared to 25.40% (16 women) in the control group. Surgery was identified as an independent factor linked to PMS improvement. Changes in BMI, testosterone, and estradiol levels were associated with symptom improvement.
What it means for you
Weight loss surgery may help some women with PMS, possibly through hormonal changes. However, some control participants also improved without surgery. Follow-up was only 3 months so longer-term effects are unknown. This is major surgery with risks.
57.35%
improvement rate in surgery group
25.40%
improvement rate in control group
3 months
follow-up duration
About the study
- Original title
- Laparoscopic sleeve gastrectomy for premenstrual syndrome symptoms in patients with obesity
- Authors
- Kong X, Zhang Y, Song K et al.
- Journal
- Surgical endoscopy
- Year
- 2024
- Study design
- Case-control study
- Participants
- 39
- What was tested
- Laparoscopic sleeve gastrectomy surgery (68 women) versus no surgery (63 women)
- Read the paper
- doi.org/10.1007/s00464-024-10819-6