Non-randomised trial, 2022
Can a simple taste test identify women with ADHD and severe PMS?
A simple taste test showed women with both ADHD and severe PMS (PMDD) did not respond to lidocaine as expected. This might point to a physical difference in how their nerve cells work.
What they did
Developed a taste test for lidocaine response. First validated it in 12 people by comparing it to injected lidocaine. Then tested it in 53 people total including those with ADHD and PMS and controls.
What they found
Women with ADHD and PMS together showed a strong association with not responding to lidocaine as expected, suggesting a biological cause related to how nerve cells work.
What it means for you
There may be a simple test to help identify women with ADHD and PMDD. This study was very small and early-stage, so it needs much more testing before it could be used in clinics.
53
Total participants (cases and controls)
12
Used to validate the test initially
About the study
- Original title
- Lidocaine Ineffectiveness Suggests New Psychopharmacology Drug Target
- Authors
- Mintz M, Badner V, Feldman LK et al.
- Journal
- Psychopharmacology bulletin
- Year
- 2022
- Study design
- Non-randomised trial
- Participants
- 53
- What was tested
- Lidocaine taste test
- Open access
- Yes
- Read the paper
- doi.org/10.64719/pb.4441
Topics
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