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Survey study, 2021

Is premenstrual syndrome linked to heart and metabolic problems like high blood pressure?

Yes, about 1 in 10 women with PMS have high blood pressure, and one study found PMS was associated with 1.4 times higher risk of developing high blood pressure. Limited research exists on how PMS relates to blood sugar levels.

Early or limited evidence Narrative review of literature (no specific population studied)

What they did

Narrative review of recent data on the relationship between premenstrual syndrome and cardio-metabolic conditions including high blood pressure and obesity.

What they found

Approximately 1 in 10 women with PMS have high blood pressure. Even with normal baseline blood pressure, menstrual cycle-related symptoms correlate with higher blood pressure (systolic and diastolic) during the luteal phase versus the follicular phase. One study found PMS was associated with a hazard ratio of 1.4 (95% CI 1.2 to 1.6) for developing high blood pressure, independent of age, smoking status and body mass index. For blood sugar, there is limited data with only small studies showing glucose and insulin differences during menstrual cycle phases. PMS seems more frequent in obese individuals but not all studies agree.

What it means for you

PMS may be linked to heart and metabolic health problems, but we don't know if PMS causes these or if both conditions just happen to occur together. Food behavior changes are part of PMS. The main limit is this is a narrative (non-systematic) review with limited data on some topics.

1 in 10

women with PMS have high blood pressure

1.4

hazard ratio for developing high blood pressure with PMS

95% CI 1.2-1.6

confidence interval for hazard ratio

About the study

Original title
Managementul tulburărilor metabolice la femei diagnosticate cu sindrom premenstrual
Authors
Eugenia Nedeltcheva Petrova, Mara Carşote, Adina Mariana Ghemigian et al.
Journal
Management in Health
Year
2021
Study design
Survey study
What was tested
None
Open access
Yes

Topics