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Survey study, 2025

Do PMS and menopausal symptoms make loneliness worse when women experience COVID-related stress?

Yes, PMS symptoms were associated with greater loneliness in pre-menopausal women with COVID-related stress, particularly through the emotional symptoms of PMS.

Early or limited evidence 530 female workers in Japan, including 303 pre-menopausal (mean age 37.0 years) and 217 post-menopausal women (mean age 57.1 years).

What they did

Cross-sectional web survey in Japan of 530 female workers (303 pre-menopausal, 217 post-menopausal). Researchers measured COVID-related PTSD symptoms and loneliness using standard scales. They assessed PMS symptoms in 263 pre-menopausal women (mean age 37.0 years, SD 8.9) and menopausal symptoms in 203 post-menopausal women (mean age 57.1 years, SD 9 0.6).

What they found

Pre-menopausal women reported higher loneliness than post-menopausal women, though this difference weakened after adjusting for age. PMS symptoms were positively associated with loneliness in pre-menopausal women. The psychological aspects of PMS symptoms were linked to increased loneliness related to COVID stress. In post-menopausal women, both PTSD symptoms and menopausal symptoms were associated with loneliness.

What it means for you

If you have PMS and experience pandemic-related stress, you may feel more isolated and lonely, especially if you experience emotional symptoms of PMS. This is a cross-sectional study so cannot prove PMS causes loneliness, and it only included female workers in Japan.

530

Female workers surveyed

263

Pre-menopausal women in PMS analysis

203

Post-menopausal women in analysis

About the study

Original title
Mediating effects of menstruation/menopause on the association between the COVID-19 pandemic related post-traumatic stress disorder symptoms and loneliness in Japanese female workers: A cross-sectional study
Authors
Hirokawa K, Noda T, Tokunaga K
Journal
European journal of obstetrics, gynecology, and reproductive biology
Year
2025
Study design
Survey study
Participants
530
Open access
Yes

Topics