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Case report, 2015

Do hormones from the menstrual cycle affect schizophrenia symptoms?

Yes. Women with schizophrenia often have worsening psychotic symptoms and depression or anxiety at certain times in their menstrual cycle. Doctors can manage this by adjusting medications.

Early or limited evidence Women diagnosed with schizophrenia

What they did

This is a review of what experts know about the relationship between menstrual cycles and schizophrenia symptoms, with a case example included. It is not a study of new treatment.

What they found

Psychotic symptoms and depression often get worse during specific parts of the menstrual cycle in women with schizophrenia. Doctors can treat worsening symptoms by using antidepressants (SSRIs), increasing antipsychotic medication 3-5 days before menstruation, or using hormone therapy to manage menstrual cycle changes.

What it means for you

Women with schizophrenia should track how their symptoms change throughout their menstrual cycle and tell their doctor about patterns. Their doctor can then adjust treatment timing to help. The evidence comes from doctors' observations and case reports rather than large controlled studies.

3-5

Days before menstruation when medication adjusted

About the study

Original title
Menstrual Cycle in Schizophrenic Patients: Review with a Case
Authors
Sönmez İ, Köşger F
Journal
Noro psikiyatri arsivi
Year
2015
Study design
Case report
What was tested
Antidepressants or antipsychotics adjusted 3-5 days before period, or hormone therapy
Open access
Yes

Topics