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Cohort study, 1989

What causes PMS symptoms?

The authors review four different theories about PMS based on hormones, heightened sensitivity, mood disorders, or problems with state regulation, but conclude that no single explanation has been proven.

Early or limited evidence Not specified; theoretical review

What they did

Literature review summarizing evidence for different theoretical models explaining how PMS develops and manifests.

What they found

Four proposed models identified: biochemical or endocrine models, symptom exaggeration or special sensitivity models, PMS as an affective disorder variant, and PMS as a disorder of state regulation. The review notes that PMS has no consistently observed biochemical or psychological markers.

What it means for you

PMS is likely complex with multiple possible causes, not a single explanation. The main limitation is that this is a 1989 review of theoretical arguments rather than new research data.

4

proposed theoretical models

About the study

Original title
Models for the development and expression of symptoms in premenstrual syndrome
Authors
Rubinow DR, Schmidt PJ
Journal
The Psychiatric clinics of North America
Year
1989
Study design
Cohort study
What was tested
None; literature review

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