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Interview study, 1983

Does mood and physical distress follow a pattern through the menstrual cycle?

Yes. Mood peaks in the late follicular phase and declines in the luteal phase. Physical distress increases in the second half of the cycle and peaks in the late luteal phase.

Early or limited evidence 55 women with normal ovulatory cycles, including one-third with severe clinic PMS, one-third with history of PMS, and one-third without PMS

What they did

Fifty-five women with normal cycles tracked mood and physical symptoms across the menstrual cycle. One-third had severe PMS, one-third had a history of PMS, and one-third had no PMS. Researchers divided each cycle into six hormonally distinct phases based on hormone measurements.

What they found

Self-ratings of well-being peaked in the late follicular phase and declined throughout the luteal half of the cycle. Physical distress increased during the second half of the cycle, reaching a maximum in the late luteal phase. This pattern was pronounced and statistically significant in women with clinic PMS and non-clinic PMS.

What it means for you

Mood and physical state are clearly linked to hormonal phases of the menstrual cycle. It remains unclear whether severe PMS represents an extreme form of normal changes or is qualitatively different. This is a small, older study without detailed comparison groups.

55

women tracked in study

6

hormonally distinct cycle phases

1/3

had clinic PMS

About the study

Original title
Mood, sexuality, hormones and the menstrual cycle. I. Changes in mood and physical state: description of subjects and method
Authors
Sanders D, Warner P, Bäckström T et al.
Journal
Psychosomatic medicine
Year
1983
Study design
Interview study
Participants
55
What was tested
None; this was an observational study

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