Review, 2010
Can neurosteroids help with anxiety and brain disorders?
The review suggests neurosteroids might help with anxiety, epilepsy, and depression, but clinical evidence is limited.
What they did
Review article examining how neurosteroids work in the brain and their potential as treatments for various conditions.
What they found
Neurosteroids are made in the brain and control brain cell activity. Allopregnanolone has powerful anti-seizure activity. Different types regulate anxiety, stress, and memory. Some synthetic versions may help anxiety and depression without benzodiazepine side effects. Clinical trials with ganaxolone for epilepsy were encouraging.
What it means for you
Synthetic neurosteroids might become treatments for anxiety and depression in the future. However, this review mainly covers basic science and early clinical research. Larger clinical trials are still needed.
About the study
- Original title
- Neurosteroids: endogenous role in the human brain and therapeutic potentials
- Authors
- Reddy DS
- Journal
- Progress in brain research
- Year
- 2010
- Study design
- Review
- What was tested
- None - this is a review article
- Open access
- Yes
- Read the paper
- doi.org/10.1016/b978-0-444-53630-3.00008-7
Topics
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