Study, 1995
What causes PMS and how can doctors treat it?
PMS develops when hormone changes interact with brain chemistry, especially involving serotonin. Medications that work on these systems have been shown to help in rigorous studies.
What they did
This is a review of research on the causes and treatment of PMS.
What they found
Evidence shows PMS results from an interaction between cyclic changes in estrogen and progesterone and brain chemical systems, particularly serotonin and GABA. Medications that disrupt the normal hormone cycle, like gonadotropin releasing hormone agonists or danazol, and medications that affect serotonin and GABA activity, like selective serotonin-reuptake inhibitors and benzodiazepines, have been shown to work in rigorous studies.
What it means for you
PMS has a biological basis involving hormones and brain chemistry. Several types of medications have good evidence for working. This is a summary of research, not a new study.
About the study
- Original title
- Pathophysiology and treatment of premenstrual syndrome
- Authors
- Joseph F. Mortola
- Journal
- Current Opinion in Endocrinology & Diabetes
- Year
- 1995
- Study design
- Study
- Read the paper
- doi.org/10.1097/00060793-199512000-00004
Topics
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