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Cohort study, 2020

How common is worsening asthma around the menstrual cycle in women with AERD?

24% of women with AERD reported menstrual asthma, meaning their asthma symptoms worsened around their period. This finding is reasonably reliable from a survey-based study.

Moderate study design 322 women 18 years and older with AERD from a hospital registry who responded to a survey.

What they did

Researchers surveyed 322 women with AERD (aspirin-exacerbated respiratory disease, a severe respiratory condition triggered by certain pain relievers) about whether menstruation triggered asthma symptoms.

What they found

74 women (24%) reported asthma worsened around menstruation. Women with menstrual asthma were more likely to have AERD start at a younger age, to have concurrent sinus symptoms around their period, to visit the emergency department for asthma more often, and to notice changes in symptom severity at menopause.

What it means for you

Many women with AERD experience worsening asthma around their period, likely because hormones affect their airways. Doctors should discuss this with patients. The study looked only at women who already had AERD, so we cannot determine whether menstrual asthma increases AERD risk.

322

women surveyed

74

women with menstrual asthma

24%

prevalence of menstrual asthma

About the study

Original title
Perimenstrual Asthma in Aspirin-Exacerbated Respiratory Disease
Authors
Eid RC, Palumbo ML, Cahill KN
Journal
The journal of allergy and clinical immunology. In practice
Year
2020
Study design
Cohort study
Participants
74
What was tested
None
Open access
Yes

Topics