Skip to content

Randomised trial, 1991

Does calcium help PMS symptoms?

Yes. Calcium reduced negative mood, water retention, and pain during the week before your period, and reduced pain during your period.

Moderate study design 33 women in a randomized controlled trial

What they did

33 women rated 14 PMS symptoms every day in a randomized, double-blind, crossover trial of calcium supplementation. The study analyzed 2,413 daily ratings during the luteal and menstrual phases using factor analysis.

What they found

Four symptom groups were identified (negative affect, water retention, food, and pain) accounting for 67% of total variance. Calcium reduced negative affect (p=.045), water retention (p=.003), and pain (p=.036) during the luteal phase. It also reduced pain (p=.02) during the menstrual phase.

What it means for you

Calcium may help with specific PMS symptoms. However, this is a small study, so results need confirmation in larger research. The crossover design is a strength because each woman served as her own control.

33

women

67%

total symptom variance explained

4

symptom clusters identified

About the study

Original title
Premenstrual and menstrual symptom clusters and response to calcium treatment
Authors
Alvir JM, Thys-Jacobs S
Journal
Psychopharmacology bulletin
Year
1991
Study design
Randomised trial
Participants
33
What was tested
Calcium supplementation

Topics