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Survey study, 2025

What health and lifestyle factors are linked to worse premenstrual symptoms?

Early first period, irregular cycles, and other health conditions including headaches, pain, diabetes, thyroid problems, and mood disorders were linked to worse symptoms.

Early or limited evidence 29 respondents from Europe who answered an online survey

What they did

Researchers created a survey and distributed it online across Europe through social media and email between November 2023 and November 2024. They collected 29 responses and analyzed them for links between lifestyle, health history, and premenstrual disorder symptoms.

What they found

66.2% reported premenstrual disorders negatively affected daily activities. Early menarche was significantly linked to more severe menstrual symptoms (p=0.0128). Irregular cycles were linked to higher rates of PMS, PMDD, and symptoms. Health conditions including headaches, chronic pain, diabetes, thyroid disorders, gynecological issues, and mood disorders were significantly associated with PMS symptoms. All 29 participants had a family history of PMS or mood disorders, with 13 having formal diagnoses.

What it means for you

Premenstrual disorders involve multiple interconnected causes including genetics, health conditions, and lifestyle. This very small study recruited online so findings may not apply widely. Results suggest each person needs individualized assessment.

29

respondents

66.2%

negatively affected daily activities

13

had formal diagnoses

About the study

Original title
Premenstrual Disorders Impact on Quality of Life
Authors
Al-Diwan D, Matuzaite G, Paliulyte V
Journal
Preprints.org
Year
2025
Study design
Survey study
Participants
29
What was tested
None, observational study
Open access
Yes
Original abstract

Background: and Objectives: Premenstrual disorders (PMDs), including premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD), significantly affect women’s health, daily functioning, and overall quality of life. This study aimed to highlight the broad impact of PMDs, raise awareness and identify key contributing factors. Materials and Methods: A specifically designed questionnaire was disseminated across Europe via social media platforms and electronic communication channels. Data were collected between November 2023 and November 2024. Responses were analyzed using R Commander software to identify significant correlations between lifestyle, health history, and PMD symptoms. Results: Statistically significant relationships were identified between lifestyle factors and both physical and psychological symptoms, as well as in-creased likelihood of PMS diagnosis (p = 0.042). Early menarche was associated with more severe menstrual symptoms (p = 0.0128), and irregular cycles correlated with higher rates of PMS, PMDD, and related symptoms. Notably, 66.2% of respondents reported PMDs negatively affected daily activities. Health conditions such as headaches, chronic pain, diabetes, thyroid disorders, gynecological issues, and mood disorders were significantly associated with PMS symptoms, including swollen breasts and food cravings. A family history of PMS and mood disorders was present in 29 participants, with 13 having formal diagnoses. Conclusions: PMDs substantially impair quality of life and are linked to a range of biological, psychological, and lifestyle factors. Findings suggest a potential genetic component and underscore the necessity for personalized, multifaceted diagnostic and treatment approaches. These results advocate for heightened societal awareness and improved clinical practices to address the wide-reaching impacts of PMDs.

Reproduced under CC-BY.

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