Review, 2026
What should doctors know about PMDD across gynecology and psychiatry?
PMDD is a serious mood disorder linked to the menstrual cycle that requires care from both gynecology and psychiatry specialists working together.
What they did
A narrative review of scientific literature on PMDD covering its epidemiology, causes, clinical presentation, diagnosis, related conditions, psychiatric complications, and treatment options.
What they found
PMDD involves affective, behavioral, cognitive, and somatic symptoms that significantly impair daily functioning. It occurs at the intersection of gynecological and psychiatric conditions. The condition is linked to ovulation, menstrual cyclicity, and ovarian hormone fluctuations.
What it means for you
PMDD is complex and needs attention from both gynecologists and psychiatrists. People with PMDD benefit from coordinated care between specialties. This is a narrative review without systematic methods, so it may not evaluate all evidence with equal rigor.
2
Specialties involved (gynecology and psychiatry)
About the study
- Original title
- Premenstrual Dysphoric Disorder as a Shared Challenge for Gynecology and Psychiatry: A Narrative Review
- Authors
- Angelika Złotnik, Ewa Wiench, Magdalena Kloc et al.
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Year
- 2026
- Study design
- Review
- What was tested
- None (narrative review)
- Open access
- Yes
- Read the paper
- doi.org/10.5281/zenodo.21368262
Original abstract
Introduction:Premenstrual dysphoric disorder (PMDD) is a severe cyclic neuroendocrine mood disorder situatedat the interface of gynecology and psychiatry. Although linked to ovulation, menstrual cyclicity, andovarian hormone fluctuations, its most disabling manifestations are often affective, behavioral,cognitive, and somatic symptoms that significantly impair daily functioning.Purpose:The aim of this narrative review was to summarize current knowledge on PMDD, with particularemphasis on epidemiology, pathophysiology, clinical presentation, diagnostic approach, differentialdiagnosis, psychiatric comorbidity, treatment options, and the need for interdisciplinary care.Materials and Methods:A narrative literature review was conducted using current clinical guidelines, diagnosticclassifications, systematic reviews, meta-analyses, and original research concerning PMDD,premenstrual syndrome, reproductive psychiatry, menstrual-cycle-related mood symptoms, andpsychiatric comorbidity. Special attention was given to evidence relevant to clinical practice ingynecology and psychiatry.
Reproduced under CC-BY.
Topics
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