Skip to content

Study, 2008

How common is PMDD and how does it affect women's lives?

About 5% of menstruating women have severe PMDD with significant impairment in functioning. At least another 20% have clinically significant premenstrual symptoms. PMDD affects romantic relationships, parenting, work, and increases health care use.

Early or limited evidence Data on menstruating women generally, describing PMDD prevalence and burden

What they did

This describes the prevalence of PMDD, its impact on women's lives and functioning, and current understanding of what causes it and how it can be treated.

What they found

Five percent of menstruating women have PMDD with impaired functioning. At least 20% have clinically significant premenstrual symptoms. Women with PMDD experience disruption in relationships and work, and use more health care services. The cause involves dysregulation of serotonin and allopregnanolone. Treatments include serotonin antidepressants, an oral contraceptive with ethinyl estradiol and drosperinone, ovulation-suppressing hormones, anti-anxiety medications, cognitive therapy, chasteberry, and calcium.

What it means for you

PMDD is a serious condition affecting millions of women with real impact on their lives and relationships. Multiple treatment options exist. Diagnosis requires careful symptom tracking over 2 menstrual cycles to confirm the cyclical pattern.

5%

menstruating women with severe PMDD

20%

with clinically significant premenstrual symptoms

2

menstrual cycles needed to diagnose

About the study

Original title
Premenstrual dysphoric disorder: burden of illness and treatment update
Authors
Pearlstein T, Steiner M
Journal
Journal of psychiatry & neuroscience : JPN
Year
2008
Study design
Study
Open access
Yes

Topics