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Cohort study, 2013

Does having PMS or PMDD before pregnancy increase the risk of postpartum depression?

Yes. Women with a history of PMS or PMDD were more likely to develop postpartum depression, especially those who had been pregnant before. The link was confirmed at 5 days, 6 weeks, and 6 months after birth.

Moderate study design 2318 women delivering at a Swedish university hospital.

What they did

Swedish hospital-based cohort study. All women delivering at a university hospital during one year (May 2006 to June 2007) were invited to participate. They completed questionnaires at 5 days, 6 weeks, and 6 months postpartum, reporting previous premenstrual symptoms and depression symptoms using the Edinburgh Postnatal Depression Scale (score of 12 or more counted as depression).

What they found

Among 2318 women, 7.1% had reported a history of premenstrual syndrome and 2.9% had reported premenstrual dysphoric disorder. Both groups showed higher rates of postpartum depression at all three follow-up times. The association remained significant only in women who had been pregnant before.

What it means for you

Women with PMS or PMDD should be monitored for postpartum depression, particularly those with prior pregnancies. The study relied on women remembering their premenstrual symptoms after giving birth and only included women at one Swedish hospital.

7.1%

Women with history of PMS

2.9%

Women with history of PMDD

2318

Total women studied

About the study

Original title
Premenstrual syndrome and dysphoric disorder as risk factors for postpartum depression
Authors
Sylvén SM, Ekselius L, Sundström-Poromaa I et al.
Journal
Acta obstetricia et gynecologica Scandinavica
Year
2013
Study design
Cohort study
Participants
2,318
What was tested
None (observational study).

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