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Survey study, 1991

Is PMS a psychiatric disorder or a gynecological disorder?

PMS is a gynecological disorder tied to ovulation and the corpus luteum, since symptoms stop when ovulation stops. Women with 'pure PMS' have less psychiatric history than other groups.

Early or limited evidence Women with menstrual cycle-related symptoms seeking medical and psychological evaluation.

What they did

Researchers classified women into three groups: Pure PMS (symptoms only before menstruation), Premenstrual aggravation (symptoms worse before menstruation), and Non-PMS (no cycle-related symptoms). They compared psychiatric history and personality traits between groups and observed what happened in women who did not ovulate and in postmenopausal women on hormone therapy.

What they found

The 'Pure PMS' group had significantly less neurosis and lower psychiatric history. In women with anovulatory cycles (no ovulation), the cyclical symptom pattern disappeared. GnRH-agonists, which stop ovulation, stopped the cyclical symptoms. Postmenopausal women on estradiol/progestagen therapy developed PMS-like symptoms when progestagen was added.

What it means for you

The corpus luteum and ovulation are central to PMS symptoms, suggesting it is fundamentally a gynecological condition. Psychological factors influence how much symptoms bother women. The study was cross-sectional and observational, so it cannot prove cause and effect.

3

subgroups identified

Anovul cycles

stopped cyclical symptoms

About the study

Original title
Premenstrual syndrome--psychiatric or gynaecological disorder?
Authors
Bäckström T, Hammarbäck S
Journal
Annals of medicine
Year
1991
Study design
Survey study
What was tested
Classification into subgroups and observation of natural cycles and treatment responses.

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