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Study, 2015

Does a birth control pill with drospirenone help reduce PMS?

Yes. The birth control pill with drospirenone produced a clear positive effect on PMS, particularly for psychological symptoms like mood changes and anxiety.

Moderate study design 122 women with moderate to severe PMS

What they did

A study of 122 women with moderate to severe PMS. Doctors confirmed the diagnosis by having women track their symptoms in a diary. Women then took a birth control pill containing 3 mg drospirenone and 20 micrograms of ethinyl estradiol, taking the pill for 24 days with 4 pill-free days in each cycle.

What they found

The birth control pill produced a pronounced positive effect on PMS, particularly for the psychological symptoms.

What it means for you

The drospirenone-containing birth control pill may help reduce psychological symptoms of PMS like mood changes, worry, and depression. The main limits are the study doesn't report specific numbers for how much symptoms improved and doesn't mention whether there was a comparison group of women not taking the pill.

122

women with moderate to severe PMS

3 mg

drospirenone dose

20 µg

ethinyl estradiol dose

About the study

Original title
Premenstrual syndrome: the effectiveness of treatment with a drospirenone-containing contraceptive
Authors
V. N. Prilepskaya, Antonina Vitalievna Ledina
Journal
DOAJ (DOAJ: Directory of Open Access Journals)
Year
2015
Study design
Study
Participants
122
What was tested
Birth control pill containing 3 mg drospirenone and 20 micrograms ethinyl estradiol
Open access
Yes
Original abstract

Premenstrual syndrome (PMS) is a frequent disorder associated with the menstrual cycle; treatments include a variety of medicinal and non-medicinal methods, primarily due to the absence of a common theory for the development of PMS. The majority of authors see premenstrual syndrome as a heterogeneous condition. Combined hormonal contraception is a pathogenetically substantiated method of PMS treatment. The study involved 122 patients with moderate to severe PMS. The diagnosis was confirmed by a prospective assessment of diaries. Participants received a drug containing 3 mg drospirenone and 20 µg ethinyl estradiol within 24/4 regimen. A pronounced positive effect of COC treatment was largely achieved in respect of psychological symptoms of PMS.

Reproduced under CC-BY-SA.

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