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Cohort study, 2002

Is jaw pain sensitivity different at different times of the menstrual cycle?

Yes. Women with jaw muscle pain are less sensitive to pressure pain in the phases before and after their period, but more sensitive to pain around menstruation itself.

Early or limited evidence 15 women with temporomandibular disorder myalgia (jaw muscle pain), 10 completed the study

What they did

15 women with jaw muscle pain (temporomandibular disorder) were tested for pain sensitivity at different points across 2 menstrual cycles. Pain was measured by seeing how much pressure they could tolerate before pain started (pressure-pain threshold), pain ratings, and descriptions of pain quality. Only 10 women completed the study.

What they found

Pain tolerance improved 16% to 42% in the follicular and luteal phases (before and after the period). Pain tolerance remained low in the perimenstrual phase (around the period). Self-reported pain ratings on a visual scale didn't match the pressure measurements well. The quality of pain (sensory, emotional, and evaluative aspects) improved by the end of the study.

What it means for you

Menstrual hormones affect how sensitive jaw muscles are to pain, with people most sensitive around their period. This is a very small study of one specific pain condition, so the findings may not apply to other types of pain or PMS in general.

15

Women with jaw muscle pain enrolled

10

Completed the study

16%-42%

Increase in pain tolerance in follicular and luteal phases

About the study

Original title
Pressure-pain threshold variation in temporomandibular disorder myalgia over the course of the menstrual cycle
Authors
Isselée H, De Laat A, De Mot B et al.
Journal
Journal of orofacial pain
Year
2002
Study design
Cohort study
Participants
15
What was tested
None; natural menstrual cycle observed

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