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Survey study, 2016

Does the ability to produce equol from soy reduce PMS risk?

Women with PMS were less likely to be equol producers than those without PMS (23.9% vs 41.8%). This suggests equol production may reduce PMS risk, but this small study cannot prove causation.

Early or limited evidence 144 Japanese women aged 20-45 with and without PMS

What they did

Researchers compared 46 women with PMS to 98 without PMS by testing their ability to produce equol (a soy compound) using urine tests after they ate soy.

What they found

Only 23.9% of women with PMS were equol producers compared to 41.8% of women without PMS. Women with PMS were 2.342 times more likely to be non-producers. Younger age was also linked to not producing equol.

What it means for you

The link between equol production and PMS is interesting but this is a small cross-sectional study from one country. We cannot tell if low equol causes PMS or if something else explains both.

23.9%

Equol producers in PMS group

41.8%

Equol producers in control group

2.342

Odds ratio for non-producers

About the study

Original title
Relation between premenstrual syndrome and equol-production status
Authors
Takeda T, Ueno T, Uchiyama S et al.
Journal
The journal of obstetrics and gynaecology research
Year
2016
Study design
Survey study
Participants
98
What was tested
Soy challenge test to assess equol production

Topics