Review, 2001
Do serotonin reuptake inhibitors help premenstrual dysphoria?
Yes, very effectively. These medications work rapidly and are more effective than non-serotonergic antidepressants.
What they did
Literature review examining the effects of serotonin reuptake inhibitors and other antidepressants on premenstrual dysphoria.
What they found
Serotonin reuptake inhibitors very effectively reduce symptoms of premenstrual dysphoria with rapid onset of action. Non-serotonergic antidepressants do not reduce symptoms. The cardinal symptom is irritability, which appears between ovulation and menstruation and disappears within a few days of menstruation.
What it means for you
Serotonin reuptake inhibitors can be used only during the luteal phase rather than continuously, which is practical for treatment. This is a literature review, so findings come from summarizing other studies rather than new research.
5-10%
Women affected by premenstrual dysphoria
About the study
- Original title
- [Serotonin uptake inhibitors provide rapid relief from premenstrual dysphoria. New findings shed light on how serotonin modulates sex hormone-related behavior]
- Authors
- Eriksson E, Andersch B, Ho HP et al.
- Journal
- Lakartidningen
- Year
- 2001
- Study design
- Review
- What was tested
- Serotonin reuptake inhibitors
- Read the paper
- https://pubmed.ncbi.nlm.nih.gov/11571794/
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