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Study, 2025

How well do SSRIs work for treating PMS and PMDD?

SSRIs are recommended as a first treatment option by Dutch guidelines when lifestyle changes have not worked well enough, usually used alongside oral contraceptives.

Early or limited evidence People with PMS and PMDD

What they did

This article reviews treatment recommendations for PMS and PMDD from the Dutch Society for Obstetrics and Gynaecology, including when to use SSRIs and oral contraceptives.

What they found

According to the Dutch guidelines, SSRIs are a first treatment option for PMS and PMDD when various lifestyle recommendations have been tried and turned out to be not or insufficiently effective. They are often used alongside oral contraceptives. The article discusses SSRIs and their intermittent use during the luteal phase.

What it means for you

SSRIs are considered a main medical treatment choice for PMS and PMDD by Dutch guidelines when lifestyle approaches don't work. A limit is that this is a summary of guidelines, not a study showing how well SSRIs actually work in real people.

About the study

Original title
SSRIs for PMS and PMDD
Authors
RW van der Zanden
Journal
Geneesmiddelenbulletin
Year
2025
Study design
Study
What was tested
SSRI treatment and oral contraceptive options
Open access
Yes

Topics