Randomised trial, 2004
Does a dietary supplement called Karinat help premenstrual syndrome and breast pain?
Yes, Karinat improved symptoms in 75.8% of women, which was 45.5 percentage points more than those taking placebo.
What they did
Double-blind randomized trial. 66 women took either Karinat (a supplement with vitamins and garlic) or placebo, twice daily for 6 months. Doctors checked their symptoms using clinical exams, breast ultrasound and mammography.
What they found
Karinat reduced breast pain, premenstrual syndrome, period pain, and other breast symptoms. The treatment group had positive results in 75.8% of women compared to being significantly greater by 45.5 percentage points relative to placebo.
What it means for you
This study shows promise but has limits. The sample was small and the supplement contained multiple ingredients, so we cannot tell which components helped. The findings need confirmation in larger studies.
66
women in study
75.8%
improved with Karinat
45.5 points
greater than placebo
About the study
- Original title
- [Study of an antioxidant dietary supplement "Karinat" in patients with benign breast disease]
- Authors
- Bespalov VG, Barash NIu, Ivanova OA et al.
- Journal
- Voprosy onkologii
- Year
- 2004
- Study design
- Randomised trial
- Participants
- 66
- What was tested
- Karinat supplement (beta-carotene 2.5mg, alpha-tocopherol 5mg, ascorbic acid 30mg, garlic powder 150mg) taken twice daily
- Read the paper
- https://pubmed.ncbi.nlm.nih.gov/15605774/
Topics
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