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Cohort study, 2026

What premenstrual symptoms do women most often seek treatment for, and does this change with age?

Fatigue and mood swings were the most common moderate-to-severe symptoms, and psychological symptoms were reported more often than physical ones. Women in their 40s were less likely to report appetite changes and food cravings than women in their 20s.

Early or limited evidence 199 women aged 20-49 seeking treatment for premenstrual symptoms at a gynecology clinic in Japan

What they did

Researchers looked back at records of 199 women, aged 20 to 49, who visited a gynecology clinic in Japan for premenstrual symptoms between November 2022 and May 2023. They checked how common 31 different premenstrual symptoms were and compared results across age groups.

What they found

Women in their 20s were the largest group, and 89.9% of them had dysmenorrhea (painful periods). Fatigue (71.9%) and mood swings (70.9%) were the most common moderate-to-severe symptoms overall. Compared with women in their 20s, women in their 40s had much lower odds of appetite changes (adjusted odds ratio 0.10), overeating (aOR 0.19), and specific food cravings (aOR 0.09).

What it means for you

Psychological symptoms like fatigue and mood swings seem to be the main reason women seek help, and appetite-related symptoms may matter less as women get older. This was a one-time look back at clinic records from a single site, not a long-term tracking study, so it cannot show how symptoms change over time for the same woman.

89.9%

Had dysmenorrhea (women in 20s)

71.9%

Reported fatigue

70.9%

Reported mood swings

About the study

Original title
Symptoms experienced by Japanese women seeking treatment for premenstrual symptoms and age-related differences: a cross-sectional study
Authors
Ogawa M, Valckx K, Iida M et al.
Journal
Fukushima journal of medical science
Year
2026
Study design
Cohort study
Participants
199
Open access
Yes

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