Systematic review, 2019
Is low magnesium linked to premenstrual syndrome?
No clear link was found between magnesium levels and PMS overall. Studies outside the United States found lower magnesium during the luteal phase in women with PMS, but the practical significance is unclear.
What they did
Systematic review and meta-analysis of 13 observational studies (from 196 identified) examining magnesium levels and PMS, searching medical databases through January 2019.
What they found
No significant association between serum magnesium and PMS in the overall analysis. In studies conducted outside the US, serum magnesium was lower in the luteal phase in women with PMS. Heterogeneity between studies suggests results should be interpreted cautiously.
What it means for you
Magnesium levels do not appear to be a major PMS factor in most populations. Findings may vary by region or measurement methods. Larger, well-designed clinical trials are needed to confirm whether magnesium treatment helps PMS.
13
studies included of 196
-0.04
mean magnesium difference overall
-0.37
mean difference in non-US studies
About the study
- Original title
- The Association Between Serum Magnesium and Premenstrual Syndrome: a Systematic Review and Meta-Analysis of Observational Studies
- Authors
- Moslehi M, Arab A, Shadnoush M et al.
- Journal
- Biological trace element research
- Year
- 2019
- Study design
- Systematic review
- What was tested
- None, observational studies
- Read the paper
- doi.org/10.1007/s12011-019-01672-z
Topics
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