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Systematic review, 2019

Does vitamin D help premenstrual syndrome?

Observational studies found no link between vitamin D levels and PMS. However, clinical trials where women took vitamin D supplements showed the supplements helped reduce PMS symptoms.

Strong study design Studies of women from various populations examining vitamin D and premenstrual syndrome

What they did

Systematic review and meta-analysis of 16 studies (from 196 identified), including observational and intervention trials examining vitamin D and PMS, searching databases through September 2018.

What they found

Observational studies showed no significant association between vitamin D levels and PMS (weighted mean difference 3.35). However, interventional studies testing vitamin D supplementation found it was effective at reducing PMS symptoms.

What it means for you

Vitamin D supplements may help PMS symptoms, even though women with PMS don't necessarily have low vitamin D levels. This suggests supplementation could have benefits beyond correcting deficiency. More research needed on optimal doses.

16

studies included of 196

5-8%

women with severe PMS

3.35

mean difference in vitamin D levels

About the study

Original title
The Association Between Vitamin D and Premenstrual Syndrome: A Systematic Review and Meta-Analysis of Current Literature
Authors
Arab A, Golpour-Hamedani S, Rafie N
Journal
Journal of the American College of Nutrition
Year
2019
Study design
Systematic review
What was tested
Vitamin D supplementation

Topics