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Systematic review, 2005

Does bright light therapy reduce depression in premenstrual dysphoric disorder?

It is uncertain. Four small trials with 55 total participants were found, but results were inconsistent and the trials had methodological limitations.

Early or limited evidence 55 participants across 4 trials with premenstrual dysphoric disorder

What they did

Systematic review and meta-analysis of randomized clinical trials of bright light therapy for PMDD. Searched six databases for trials. Four crossover trials met inclusion criteria.

What they found

Four crossover trials studied a total of 55 participants. Three higher quality trials showed a small pooled effect size of -0.20. One fully unblinded trial showed a much larger effect. Confidence intervals were wide, and methodologic limitations were present.

What it means for you

The trials were too small and had methodological problems, so we cannot be confident whether bright light therapy works for PMDD depression. The evidence justifies neither enthusiastic support nor confident rejection of this treatment.

4

Number of randomized trials found

55

Total participants studied

-0.20

Pooled effect size from higher quality trials

About the study

Original title
The effect of bright light therapy on depression associated with premenstrual dysphoric disorder
Authors
Krasnik C, Montori VM, Guyatt GH et al.
Journal
American journal of obstetrics and gynecology
Year
2005
Study design
Systematic review
What was tested
Bright light therapy

Topics