Skip to content

Survey study, 2015

Does lower estrogen during menopause cause depression and anxiety?

Women going through menopause who had depression had lower estrogen levels than those without depression, suggesting a link. The very small sample means we cannot prove this causes depression.

Early or limited evidence 30 women going through menopause

What they did

Measured estrogen hormone levels and checked for depression and anxiety symptoms in 30 women going through menopause with irregular periods.

What they found

Women with depression had clearly lower estrogen levels than women without depression. Hot flushes, body weight, smoking, age, and PMS levels were similar between the two groups.

What it means for you

Lower estrogen during menopause may be connected to depression. The main limits are the very small sample of 30 women and this being a one-time study, so other causes cannot be ruled out.

30

women studied

20

FSH IU threshold

About the study

Original title
The effect of perimenopausal estrogen levels on depression and anxiety: a pilot study
Authors
Buket Belkız Güngör, Mahmut Gungor, İbrahim Taymur et al.
Journal
The European Research Journal
Year
2015
Study design
Survey study
Participants
30
Open access
Yes

Topics