Case-control study, 2019
Do women with sickle cell disease have more severe PMS symptoms than other women?
Women with sickle cell disease had similar rates and severity of PMS as healthy women (68% versus 78%). However, they showed lower depression scores related to PMS, possibly because they are accustomed to more severe chronic pain.
What they did
Case-control study comparing 50 women with sickle cell disease to 50 healthy women, all aged 18 years or older. Both groups completed a 21-item questionnaire and the Premenstrual Syndrome Scale to assess PMS frequency and severity from January to March 2018.
What they found
PMS was found in 68% (34 women) of the sickle cell group and 78% (39 women) of the control group. Mean depressive effect subscale scores were lower in the sickle cell group (15.64 plus or minus 6.56 versus 19.48 plus or minus 6.67).
What it means for you
Women with sickle cell disease do not appear to suffer worse PMS than other women. The lower depression scores might reflect that they already manage more severe chronic pain. This was a small single-hospital study, so results may not apply widely.
68% vs 78%
PMS prevalence in sickle cell versus control groups
15.64 vs 19.48
Depressive subscale scores (SD 6.56 vs 6.67)
50 vs 50
Study sample size
About the study
- Original title
- The Severity of Premenstrual Syndrome Symptoms in Sickle Cell Disease Patients: A Case- Control Study
- Authors
- Pınar Döner, Sabahat USLUSOY, Gül İlhan et al.
- Journal
- Konuralp Tıp Dergisi
- Year
- 2019
- Study design
- Case-control study
- Participants
- 50
- What was tested
- No intervention; groups compared for PMS characteristics
- Open access
- Yes
- Read the paper
- doi.org/10.18521/ktd.521303
Topics
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