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Survey study, 1999

Do cyclical behavioral changes happen in women with mental disabilities, and what helps?

Cyclical behavioral changes occur in 18% of women with mental disabilities. NSAIDs helped 65% of those treated, hormone injections helped 66%, and birth control pills helped 40%.

Early or limited evidence 522 women of reproductive age with mental disabilities

What they did

Doctors reviewed medical records of 522 women with mental disabilities of reproductive age who visited a clinic. They looked for cyclical behavioral changes and documented what treatments were used and whether women improved.

What they found

93 women (18%) showed cyclical behavioral changes, most commonly aggression or self-harm. Of 46 women given NSAIDs, 30 (65%) improved. Of 9 women given hormone injections (depomedroxyprogesterone), 6 (66%) improved. Of 15 given birth control pills, 6 (40%) improved.

What it means for you

Cyclical behavioral changes are common and may relate partly to menstrual pain or cramps, since NSAIDs work for most women. Hormone-based treatments also help many women when pain relievers don't. The main limit is that treatments were chosen by individual doctors rather than assigned randomly, and behavior was clearly documented in only 46% of cases.

522

Women studied

18%

With cyclical behavioral changes

65%

Improved on NSAIDs

About the study

Original title
The treatment of cyclical behavioral changes in women with mental disabilities
Authors
Quint EH, Elkins TE, Sorg CA et al.
Journal
Journal of pediatric and adolescent gynecology
Year
1999
Study design
Survey study
Participants
522
What was tested
NSAIDs, birth control pills, depomedroxyprogesterone hormone injections

Topics