Non-randomised trial, 2024

Can theta burst transcranial magnetic stimulation help treat PMDD?

The study results are not provided in this abstract, which only contains background information. Theta burst stimulation may be promising based on its effectiveness for depression.

Early or limited evidence Not specified in the provided abstract

What they did

Open-label pilot study using theta burst transcranial magnetic stimulation (a type of brain stimulation) to treat PMDD symptoms. Sample size and methods not specified in the provided abstract.

What they found

No results are included in the abstract. Background information states that PMDD is a depressive disorder occurring in a cyclical pattern due to hormonal changes, with symptoms most severe in the premenstrual phase. Existing treatments provide limited relief. Theta burst stimulation has shown effectiveness in treating depression and may be promising for PMDD symptoms.

What it means for you

This appears to be very early stage research with no actual findings reported. Cannot draw conclusions about effectiveness. The main limitation is that this is an open-label pilot study where everyone knew they received treatment with no control group. The abstract provided is incomplete and lacks methods and results sections.

About the study

Original title: THETA BURST TRANSCRANIAL MAGNETIC STIMULATION TO TREAT PREMENSTRUAL DYSPHORIC DISORDER: AN OPEN LABEL PILOT STUDY
Authors: Elizabeth H. X. Thomas, Caroline Gurvich, Leo Chen
Journal: Transcranial magnetic stimulation .
Year: 2024
Study design: Non-randomised trial
What was tested: Theta burst transcranial magnetic stimulation
Open access: Yes
Read the paper: doi.org/10.1016/j.transm.2024.100005

Topics

Major depressive disorder Menstrual cycle and mood Premenstrual dysphoric disorder (PMDD)Low mood and depression

Cohort study, 2026

What genetic factors are linked to premenstrual symptoms?

Randomised trial, 2025

Does taking an antidepressant only during the second half of your cycle reduce anger and aggression in PMDD?

Systematic review, 2023

Is PMDD linked to depression?

Randomised trial, 2000

Does sertraline improve how women with PMDD feel and function?

Study, 2026

Do anxiety and depression get worse before your period if you already have a mental health condition?