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Cohort study, 2017

How can doctors reliably diagnose PMDD using a standardized method?

A new scoring system called C-PASS accurately diagnoses PMDD when women track their symptoms daily for two or more months, matching expert clinician diagnoses 98% of the time.

Moderate study design 200 women with reported premenstrual emotional symptoms who completed 2 to 4 months of daily symptom tracking.

What they did

Researchers created a scoring system (C-PASS) that turns daily symptom ratings into a PMDD diagnosis. They tested it on 200 women who reported premenstrual emotional symptoms by comparing C-PASS diagnosis to diagnoses made by expert clinicians.

What they found

C-PASS diagnosis matched expert clinical diagnosis 98% of the time. Women's memory of how bad their premenstrual symptoms were (guessing without daily tracking) was a poor predictor of whether they actually had PMDD.

What it means for you

This provides a clear, standardized way to diagnose PMDD that reduces confusion in research and clinical practice. It may help doctors diagnose PMDD more consistently. The main limit is that the study was relatively small and involved women specifically recruited for having premenstrual emotional symptoms, so findings may not apply to all women seeking a PMDD diagnosis.

200

Women evaluated

98%

Correct diagnosis rate

2-4 months

Duration of daily tracking

About the study

Original title
Toward the Reliable Diagnosis of DSM-5 Premenstrual Dysphoric Disorder: The Carolina Premenstrual Assessment Scoring System (C-PASS)
Authors
Eisenlohr-Moul TA, Girdler SS, Schmalenberger KM et al.
Journal
The American journal of psychiatry
Year
2017
Study design
Cohort study
What was tested
C-PASS diagnostic scoring system
Open access
Yes

Topics