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Study, 2000

What causes PMDD and how should it be treated?

PMDD is an intense version of the normal mood and physical changes that happen before menstruation, involving genetics, brain chemistry and hormones. SSRI medications are now used as a treatment.

Early or limited evidence Not applicable - this is a review article

What they did

Researchers reviewed what premenstrual dysphoric disorder is, its causes, and how medical understanding of it has changed over time from ancient times through modern psychiatry.

What they found

PMDD involves genetic, neurobiological and hormone-related factors. A brain chemical called serotonin plays an important role. SSRI medications have become a standard treatment. Throughout history, menstruation has been misunderstood and stigmatized in many cultures.

What it means for you

Understanding that PMDD has biological causes helps move beyond outdated and stigmatizing beliefs about menstruation. More treatment options are now available. The limitation is that this is a review of existing knowledge rather than new research, so more studies are needed to fully understand all the causes.

About the study

Original title
Trastorno disfórico premenstrual
Authors
Andrea López-Mato, Gonzalo Illa, Oscar Boullosa et al.
Journal
Revista chilena de neuro-psiquiatría
Year
2000
Study design
Study
Open access
Yes

Topics